Description

7-Oxo-3,7-Dihydropyrano[3,2-E]Indole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic chemistry for constructing intricate indole- and pyran-fused heterocyclic systems.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays due to its specific molecular architecture.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials or niche APIs.

Basic Information

Product Name	7-Oxo-3,7-Dihydropyrano[3,2-E]Indole-2-Carboxylic Acid
CAS No.	343595-31-3
Molecular Formula	C12H7NO4
Molecular Weight	229.19 g/mol
Synonyms	7-Oxo-3,7-dihydropyrano[3,2-e]indole-2-carboxylic acid; Pyrano[3,2-e]indole-2-carboxylic acid, 3,7-dihydro-7-oxo-; 3,7-Dihydro-7-oxopyrano[3,2-e]indole-2-carboxylic Acid; 7-Oxo-3,7-dihydro-2H-pyrano[3,2-e]indole-2-carboxylic acid; 2-Carboxy-7-oxo-3,7-dihydropyrano[3,2-e]indole
EINECS	Contact for details

Quality Control

Our production of 7-Oxo-3,7-Dihydropyrano[3,2-E]Indole-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.