Description

5-Chloro-1,2-oxazole-3-carboxylic acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a halogenated oxazole ring, enabling its use as a key precursor for constructing complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of novel drug candidates, particularly for constructing fused heterocyclic systems.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxazole scaffold.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis or as a building block for functionalized catalysts.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of novel polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Chloro-1,2-oxazole-3-carboxylic Acid
CAS No.	343566-57-4
Molecular Formula	C4H2ClNO3
Molecular Weight	147.52 g/mol
Synonyms	5-Chloro-1,2-oxazole-3-carboxylic acid; 3-Carboxy-5-chloro-1,2-oxazole; 5-Chloroisoxazole-3-carboxylic acid; 5-Chloro-3-carboxyisoxazole; 343566-57-4; 5-Chlorooxazole-3-carboxylic acid; 5-Chloro-1,2-oxazole-3-carboxylicacid; 5-Chloro-isoxazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-1,2-oxazole-3-carboxylic acid is produced and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and consistency for your research and development processes. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.