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(2S,3S)-4-Bromo-cis-2,3-Epoxybutyl (1S)- 10-Camphorsulfonate CAS NO 343338-27-2
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CAS No.:343338-27-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2S,3S)-4-Bromo-cis-2,3-Epoxybutyl (1S)-10-Camphorsulfonate is a high-purity, chiral building block and resolving agent of significant importance in asymmetric synthesis. Its value lies in its ability to induce chirality and act as a key intermediate in the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral auxiliaries and intermediates.
Application
- Chiral Auxiliary in Asymmetric Synthesis: Used to control stereochemistry in the synthesis of complex organic molecules, enabling the production of single enantiomer products.
- Pharmaceutical Intermediate: Serves as a critical building block in the development and manufacturing of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific biological pathways.
- Resolution Agent: Employed for the separation of racemic mixtures into their individual enantiomers, a crucial step in producing optically pure compounds.
- Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, pesticides, and fungicides where biological activity is often specific to one isomer.
- Catalyst and Ligand Precursor: Acts as a starting material for synthesizing specialized chiral catalysts and ligands used in homogeneous catalysis.
- Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new synthetic routes in process chemistry.
Basic Information
| Item | Detail |
|---|---|
| Product Name | (2S,3S)-4-Bromo-cis-2,3-Epoxybutyl (1S)-10-Camphorsulfonate |
| CAS No. | 343338-27-2 |
| Molecular Formula | C₁₄H₂₁BrO₅S |
| Molecular Weight | 381.29 g/mol |
| Synonyms | (1S)-(-)-10-Camphorsulfonic Acid (2S,3S)-4-Bromo-2,3-epoxybutyl Ester; (2S,3S)-4-Bromo-2,3-epoxybutyl (1S)-camphorsulfonate; 4-Bromo-2,3-epoxybutyl camphorsulfonate; Bromoepoxybutyl camphorsulfonate; Chiral epoxy sulfonate ester; (1S)-10-Camphorsulfonic acid, 4-bromo-2,3-epoxybutyl ester, (2S,3S)- |
| EINECS | Contact for details |
Quality Control
Our (2S,3S)-4-Bromo-cis-2,3-Epoxybutyl (1S)-10-Camphorsulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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