Description

4-Bromo-2-(1-Hydroxyethyl)Phenol is a versatile brominated phenolic intermediate featuring both a phenolic hydroxyl and a secondary alcohol functional group. This bifunctional structure makes it a valuable synthon for constructing complex molecules in advanced organic synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the phenolic core is essential for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Modification Agent: Can be incorporated into polymer chains to impart flame retardancy, UV stabilization, or to introduce reactive sites for further cross-linking.
• Organic Synthesis Reagent: Utilized in various coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protecting group scaffold in multi-step synthetic routes.
• Bioconjugation & Linker Chemistry: The reactive hydroxyl groups enable its use in creating chemical linkers for attaching drugs to antibodies or other biomolecules (ADC research).

Basic Information

Product Name	4-Bromo-2-(1-Hydroxyethyl)Phenol
CAS No.	342880-86-8
Molecular Formula	C8H9BrO2
Molecular Weight	217.06 g/mol
Synonyms	2-(1-Hydroxyethyl)-4-bromophenol; 4-Bromo-2-(1-hydroxyethyl)phenol; 1-(4-Bromo-2-hydroxyphenyl)ethanol; 2-Hydroxy-5-bromo-α-methylbenzyl alcohol; 4-Bromo-2-(α-hydroxyethyl)phenol; 4-Bromo-2-hydroxyphenethyl alcohol (related); BHPE (abbreviation); CAS 342880-86-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(1-Hydroxyethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.