Description

Bicyclo[3.1.0]Hexan-3-One, 4-Methyl-1-(1-Methylethenyl)-, (1R,4S,5R)- (9Ci) is a high-purity, chiral bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique and rigid fused-ring structure, featuring defined stereochemistry, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in projects targeting central nervous system (CNS) or anti-infective drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides where its bicyclic scaffold can contribute to unique biological activity and selectivity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing specialty aroma chemicals with complex, woody, or camphoraceous notes due to its bicyclic framework.
• Material Science Research: Employed as a monomer or cross-linking agent in academic and industrial research for developing polymers with specific thermal or mechanical properties.
• Asymmetric Catalysis Ligand Precursor: Its chiral structure can be functionalized to create novel ligands for asymmetric hydrogenation or other catalytic transformations.
• Academic & Contract Research: A valuable tool for methodological studies in organic synthesis, including cycloaddition reactions and stereoselective transformations.

Basic Information

Item	Detail
Product Name	Bicyclo[3.1.0]Hexan-3-One, 4-Methyl-1-(1-Methylethenyl)-, (1R,4S,5R)- (9Ci)
CAS No.	342614-24-8
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(1R,4S,5R)-4-Methyl-1-(prop-1-en-2-yl)bicyclo[3.1.0]hexan-3-one; (-)-4-Methyl-1-(1-methylethenyl)bicyclo[3.1.0]hexan-3-one; (1R,4S,5R)-4-Methyl-1-isopropenylbicyclo[3.1.0]hexan-3-one; Chiral Bicyclo[3.1.0]hexanone derivative; 1-Isopropenyl-4-methylbicyclo[3.1.0]hexan-3-one (enantiomer); (1R,4S,5R)-rel-4-Methyl-1-(1-methylethenyl)bicyclo[3.1.0]hexan-3-one
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.0]Hexan-3-One, 4-Methyl-1-(1-Methylethenyl)-, (1R,4S,5R)- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet your specific research or production requirements. A detailed Certificate of Analysis (COA) including results from chiral HPLC, GC, NMR, and optical rotation is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Allow the container to reach room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.