Description

4-(3-Methoxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D and fine chemical synthesis teams need this material to develop next-generation drug candidates with high specificity and efficacy. Our supply ensures the consistent quality and purity required for sensitive downstream chemical processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially in central nervous system (CNS) and anti-inflammatory research.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing novel quinoline and tetrahydroquinoline derivatives due to its reactive nitrile and ketone functional groups.
• Agrochemical Research: Employed in the development of new agrochemicals, where the quinoline core can contribute to biological activity.
• Material Science Chemistry: Acts as a specialty monomer or additive in the research of advanced organic materials, such as dyes or photoactive compounds.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and process development for client-specific molecules.

Basic Information

Product Name	4-(3-Methoxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	342046-22-4
Molecular Formula	C21H22N2O2
Molecular Weight	334.42 g/mol
Synonyms	5-Oxo-4-(3-methoxyphenyl)-2,7,7-trimethyl-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; 3-Cyano-4-(3-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline; 4-(3-Methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; Hexahydroquinolinecarbonitrile derivative; AQ-CN Intermediate
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Methoxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support our clients' regulatory needs with comprehensive documentation traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.