Description

2-[(4-Fluorobenzyl)Sulfonyl]Benzoic Acid is a high-purity, functionalized benzoic acid derivative designed for advanced chemical synthesis and pharmaceutical research. This compound serves as a critical building block and intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate a sulfonyl-linked fluorobenzyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom and sulfone group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for creating labeled compounds and probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Item	Details
Product Name	2-[(4-Fluorobenzyl)Sulfonyl]Benzoic Acid
CAS No.	341933-13-9
Molecular Formula	C14H11FO4S
Molecular Weight	294.30 g/mol
Synonyms	2-[(4-Fluorophenyl)methyl]sulfonylbenzoic acid; Benzoic acid, 2-[(4-fluorobenzyl)sulfonyl]-; 2-((4-Fluorobenzyl)sulfonyl)benzoic acid; 4-Fluoro-α-[(2-carboxyphenyl)sulfonyl]methylbenzene; 2-(4-Fluorobenzylsulfonyl)benzoic Acid; [2-[(4-Fluorophenyl)methylsulfonyl]phenyl]formic acid
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Fluorobenzyl)Sulfonyl]Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and IR spectroscopy. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.