Description

Dichloro[1,3-Bis(2,4,6-Trimethylphenyl)-2-Imidazolidinylidene](3-Phenyl-1H-Inden-1-Ylidene)(Triphenylphosphine)Ruthenium(II) is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst. This compound matters for its exceptional activity, selectivity, and thermal stability in challenging cross-metathesis and ring-closing metathesis (RCM) reactions. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex molecules and polymers.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for constructing complex macrocyclic and heterocyclic ring systems via Ring-Closing Metathesis (RCM).
• Agrochemical Active Ingredient Production: Enables efficient synthesis of novel, structurally complex active ingredients through cross-metathesis.
• Advanced Polymer & Material Science: Facilitates the synthesis of specialty polymers, including functionalized polyolefins and dendrimers, via Acyclic Diene Metathesis (ADMET) and Ring-Opening Metathesis Polymerization (ROMP).
• Fine Chemical & Fragrance Manufacturing: Used in the precise construction of olefinic intermediates for high-value fine chemicals and aroma compounds.
• Academic & Industrial R&D: A staple catalyst in research laboratories for methodology development and the synthesis of novel organic frameworks.
• Process Chemistry Optimization: Valued for its robustness and tolerance to functional groups, enabling scalable, efficient manufacturing routes.

Basic Information

Product Name	Dichloro[1,3-Bis(2,4,6-Trimethylphenyl)-2-Imidazolidinylidene](3-Phenyl-1H-Inden-1-Ylidene)(Triphenylphosphine)Ruthenium(II)
CAS No.	340810-50-6
Molecular Formula	C54H55Cl2N2PRu
Molecular Weight	918.96 g/mol
Synonyms	Grubbs-Hoveyda Catalyst 2nd Generation; Hoveyda-Grubbs Catalyst II; (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(3-phenyl-1H-inden-1-ylidene)(triphenylphosphine)ruthenium(II); HG II Catalyst; Zhan Catalyst 1B; Ru-IndenyliDene Catalyst; [RuCl2(IMesH2)(PCy3)(Ind)]; CAS 340810-50-6
EINECS	Contact for details

Quality Control

Every batch of our Grubbs-Hoveyda II catalyst is manufactured and tested under stringent quality protocols to ensure consistent, high-performance material suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, metal content, and solvent residues. Our quality system is designed to support cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, freezer-safe environment. This compound is easily oxidized and hygroscopic; prolonged exposure to air, moisture, or ambient temperature will lead to decomposition and loss of catalytic activity.

Specification

Item	Specification
Appearance	Dark green to purple crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Ruthenium Content	10.5 - 11.5 %
Solvent Residue (GC)	≤ 2.0% (combined)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.