Description

(R)-3-Amino-3-Phenylpropanoic Acid Ethyl Ester Hydrochloride is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its enantiopure (R)-configuration provides critical stereochemical control in the development of targeted therapeutics, making it a valuable asset for research and production. This compound is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-amino acid derivatives and peptidomimetics.
• API Development: Building block in the research and production of potential central nervous system (CNS) agents and other biologically active molecules.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce the (R)-3-amino-3-phenylpropanoate moiety.
• Medicinal Chemistry Research: A crucial starting material for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.
• Academic & Contract Research: Serves as a standard reagent in university laboratories and CROs (Contract Research Organizations) for methodological development.

Basic Information

Product Name	(R)-3-Amino-3-Phenylpropanoic Acid Ethyl Ester Hydrochloride
CAS No.	340188-50-3
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	Ethyl (R)-3-Amino-3-phenylpropanoate hydrochloride; (R)-3-Amino-3-phenylpropionic acid ethyl ester hydrochloride; (R)-3-Phenyl-β-alanine ethyl ester hydrochloride; (R)-Ethyl 3-amino-3-phenylpropionate hydrochloride; (R)-β-Amino-β-phenylpropionic acid ethyl ester HCl; (R)-3-Amino-3-phenylpropanoate ethyl ester HCl; (R)-H-Phe-OEt·HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-Phenylpropanoic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. We adhere to industry best practices, and specifications can be tailored to meet specific project requirements, including those for cGMP (current Good Manufacturing Practice) applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.