Description

2-(5-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylpyridine and benzoic acid hybrid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), where its specific molecular architecture imparts desirable metabolic stability and bioavailability. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drugs, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Investigated for the development of organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-(5-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid
CAS No.	339538-61-3
Molecular Formula	C13H8F3NO2
Molecular Weight	267.20 g/mol
Synonyms	[2-(5-Trifluoromethyl-2-pyridinyl)]benzoic acid; 2-[5-(Trifluoromethyl)pyridin-2-yl]benzoic acid; 2-(5-(Trifluoromethyl)-2-pyridinyl)benzoic Acid; Benzoic acid, 2-[5-(trifluoromethyl)-2-pyridinyl]-; 2-(5-Trifluoromethylpyridin-2-yl)benzoic acid; 2-(5-(Trifluoromethyl)-2-pyridyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 2-(5-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support development and commercial scale requirements under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.