Description

2-[(4-Chlorobenzyl)Sulfanyl]-3-Methyl-6-(Trifluoromethyl)-4(3H)-Pyrimidinone CAS NO 339101-38-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidinone core functionalized with chlorobenzyl and trifluoromethyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced biological activity and metabolic stability. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidinone scaffold.
• Chemical Biology Research: Used as a probe or building block in studying enzyme inhibition and protein-ligand interactions.
• Material Science: Potential application in the synthesis of specialty polymers and advanced organic electronic materials due to its aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Item	Details
Product Name	2-[(4-Chlorobenzyl)Sulfanyl]-3-Methyl-6-(Trifluoromethyl)-4(3H)-Pyrimidinone
CAS No.	339101-38-1
Molecular Formula	C13H10ClF3N2OS
Molecular Weight	334.74 g/mol
Synonyms	2-[(4-Chlorobenzyl)thio]-3-methyl-6-(trifluoromethyl)-4(3H)-pyrimidinone; 2-((4-Chlorobenzyl)thio)-3-methyl-6-(trifluoromethyl)pyrimidin-4(3H)-one; 339101-38-1; 4(3H)-Pyrimidinone, 2-[(4-chlorophenyl)methyl]thio-3-methyl-6-(trifluoromethyl)-; 2-(4-Chlorobenzylsulfanyl)-3-methyl-6-trifluoromethyl-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Chlorobenzyl)Sulfanyl]-3-Methyl-6-(Trifluoromethyl)-4(3H)-Pyrimidinone is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.