Description

2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate with significant synthetic utility. This compound matters as a critical building block in the pharmaceutical industry for the development of novel therapeutic agents targeting inflammation and pain. It is primarily needed by R&D chemists and process development scientists in pharmaceutical manufacturing, as well as by fine chemical suppliers serving the global API production sector. The material is supplied with full traceability and documentation to support rigorous quality standards.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced NSAID candidates and other bioactive molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the scaled-up production of target drug substances under GMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.

Basic Information

Product Name	2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetic Acid
CAS No.	339098-92-9
Molecular Formula	C13H9FO3S
Molecular Weight	264.27 g/mol
Synonyms	2-(5-(2-Fluorobenzoyl)thiophen-2-yl)acetic acid; 2-(5-(2-Fluorobenzoyl)-2-thienyl)ethanoic acid; 2-Fluoro-α-oxo-2-thiopheneacetic acid, 5-benzoyl-; 339098-92-9; 2-[5-(2-Fluorobenzoyl)thiophen-2-yl]acetic acid; 5-(2-Fluorobenzoyl)thiophene-2-acetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for identity, purity, and impurity profiles. We support customer audits and can provide documentation to meet the requirements of cGMP, ICH Q7, and REACH compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.