Description

2-Methoxy-4-([2-(Trifluoromethyl)-4-Quinazolinyl]Oxy)Benzenecarbaldehyde is a high-value, advanced pharmaceutical intermediate characterized by its unique quinazoline and benzaldehyde functional groups. This compound is critical for the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research, where its trifluoromethyl group enhances metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinazoline-based drug candidates targeting specific kinases and enzymes.
• Oncology Research: Used in the development of small-molecule inhibitors for cancer therapy, leveraging its structural motif common in tyrosine kinase inhibitors.
• Antiviral Agent Development: Serves as a precursor in the research and synthesis of compounds with potential activity against viral proteases.
• Chemical Biology & Proteomics: Utilized as a molecular probe or scaffold for studying protein-ligand interactions and enzyme mechanisms.
• Agrochemical Research: Intermediate in the development of new-generation herbicides and pesticides with improved selectivity.
• Material Science: Potential precursor for specialty polymers or liquid crystals due to its rigid, aromatic structure and functional groups.

Basic Information

Product Name	2-Methoxy-4-([2-(Trifluoromethyl)-4-Quinazolinyl]Oxy)Benzenecarbaldehyde
CAS No.	339018-54-1
Molecular Formula	C₁₇H₁₁F₃N₂O₃
Molecular Weight	348.28 g/mol
Synonyms	4-Formyl-3-methoxyphenyl 2-(trifluoromethyl)quinazolin-4-yl ether; 2-Methoxy-4-[(2-trifluoromethyl-4-quinazolinyl)oxy]benzaldehyde; 4-[2-(Trifluoromethyl)quinazolin-4-yl]oxy-2-methoxybenzaldehyde; 339018-54-1; 2-Methoxy-4-((2-(trifluoromethyl)quinazolin-4-yl)oxy)benzaldehyde; 4-(2-Trifluoromethyl-quinazolin-4-yloxy)-2-methoxy-benzaldehyde; 2-Methoxy-4-[(2-(trifluoromethyl)-4-quinazolinyl)oxy]benzaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-Methoxy-4-([2-(Trifluoromethyl)-4-Quinazolinyl]Oxy)Benzenecarbaldehyde adheres to stringent quality protocols under a cGMP-compliant quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.