Description

1,8-Naphthyridine,7-(4-Nitrophenoxy)-2,4-Bis(Trifluoromethyl)-(9Ci) is a high-value, multi-functional heterocyclic compound distinguished by its naphthyridine core and strategically positioned trifluoromethyl and nitrophenoxy substituents. This molecular architecture makes it a critical advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, where it serves as a key building block for developing new active ingredients. The compound, identified by CAS 338978-20-4, is supplied to meet the stringent purity and consistency requirements of modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the naphthyridine scaffold.
• Material Science Precursor: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its electron-deficient aromatic system.
• Ligand Synthesis: Employed in the creation of complex chelating ligands for catalysis and metal-organic framework (MOF) construction.
• Fluorescent Probe Development: Utilized in designing molecular probes and sensors for biochemical assays and diagnostic applications.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	1,8-Naphthyridine,7-(4-Nitrophenoxy)-2,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	338978-20-4
Molecular Formula	C₁₇H₇F₆N₃O₃
Molecular Weight	415.25 g/mol
Synonyms	7-(4-Nitrophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 2,4-Bis(trifluoromethyl)-7-(4-nitrophenoxy)-1,8-naphthyridine; 1,8-Naphthyridine, 7-(4-nitrophenoxy)-2,4-bis(trifluoromethyl)-; 338978-20-4; 7-(p-Nitrophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine,7-(4-Nitrophenoxy)-2,4-Bis(Trifluoromethyl)-(9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or development specifications. Our commitment is to deliver material of consistent high purity and reliable performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure maximum stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.