Description

1-(4-Chlorophenyl)-3-[3-Chloro-2-Thioxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty agrochemicals.

Application

• Key intermediate in the research and development of novel pharmaceutical compounds, especially kinase inhibitors and other targeted therapies.
• Building block for the synthesis of agrochemicals, including potential herbicides and fungicides with specific activity.
• Precursor in organic synthesis for creating complex molecules with thioxopyridine and propenone moieties.
• Used in academic and industrial R&D for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Starting material for the preparation of specialty fine chemicals and custom synthesis projects.
• Potential intermediate for dye and pigment research, leveraging its conjugated system.

Basic Information

Product Name	1-(4-Chlorophenyl)-3-[3-Chloro-2-Thioxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]-2-Propen-1-One
CAS No.	338953-40-5
Molecular Formula	C15H8Cl2F3NO2S
Molecular Weight	390.20 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(3-chloro-2-thioxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl)prop-2-en-1-one; 2-Propen-1-one, 1-(4-chlorophenyl)-3-[3-chloro-2-thioxo-5-(trifluoromethyl)-1(2H)-pyridinyl]-; (E)-1-(4-Chlorophenyl)-3-(3-chloro-2-thioxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl)prop-2-en-1-one; CAS 338953-40-5; 1-(p-Chlorophenyl)-3-[3-chloro-2-thioxo-5-(trifluoromethyl)-2H-pyridin-1-yl]prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-3-[3-Chloro-2-Thioxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]-2-Propen-1-One is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.