Description

1,8-Naphthyridine-2-Acetonitrile,α-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci) is a high-value, fluorinated naphthyridine derivative serving as a critical synthetic intermediate. Its core value lies in enabling the development of advanced materials and pharmaceuticals by providing a complex, multi-functional scaffold. This compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical synthesis, and materials science, where its unique trifluoromethylated structure imparts desirable properties like metabolic stability and lipophilicity to target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research, leveraging the naphthyridine core's bioactivity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in display and lighting technologies due to its rigid, conjugated structure.
• Ligand Synthesis for Catalysis: Acts as a precursor for creating sophisticated nitrogen-containing ligands used in transition metal catalysis for fine chemical production.
• Fluorinated Liquid Crystal Research: Investigated as a component in the development of new fluorinated liquid crystal materials for advanced display applications.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	1,8-Naphthyridine-2-Acetonitrile,α-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci)
CAS No.	338791-75-6
Molecular Formula	C19H9F6N3
Molecular Weight	393.29 g/mol
Synonyms	α-Phenyl-5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-acetonitrile; 2-[Phenyl(5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl)methyl]acetonitrile; 5,7-Bis(trifluoromethyl)-α-phenyl-1,8-naphthyridine-2-acetonitrile; 338791-75-6; 1,8-Naphthyridine-2-acetonitrile, α-phenyl-5,7-bis(trifluoromethyl)-; (9CI)
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-2-Acetonitrile,α-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure high consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.