Description

2-(3-Chloro-5-(Trifluoromethyl)-2-Pyridylthio)Acetic Acid is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. Its core value lies in its unique molecular structure, which combines a pyridine ring with chloro and trifluoromethyl substituents linked via a thioacetic acid moiety, enabling precise synthesis of complex target molecules. This compound is essential for research and development chemists and process engineers in the agrochemical and pharmaceutical industries, particularly for creating novel active ingredients with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl groups.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities, structure-activity relationships (SAR), and novel heterocyclic compounds.
• Ligand and Catalyst Development: The pyridylthio moiety can be utilized to create specialized ligands for metal catalysis or as a scaffold in organocatalysis.
• Material Science Precursor: Potential use in synthesizing functionalized polymers or organic electronic materials due to its electron-withdrawing substituents.

Basic Information

Product Name	2-(3-Chloro-5-(Trifluoromethyl)-2-Pyridylthio)Acetic Acid
CAS No.	338422-73-4
Molecular Formula	C8H5ClF3NO2S
Molecular Weight	271.64 g/mol
Synonyms	2-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfanyl]acetic acid; Acetic acid, 2-[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)thio]-; 3-Chloro-5-(trifluoromethyl)pyridine-2-thiol acetic acid derivative; [3-Chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanylacetic acid; 2-(3-Chloro-5-trifluoromethyl-2-pyridylthio)acetic acid; 2-(3-Chloro-5-trifluoromethylpyridin-2-ylthio)acetic acid; CAS 338422-73-4
EINECS	Contact for details

Quality Control

Our production of 2-(3-Chloro-5-(Trifluoromethyl)-2-Pyridylthio)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.