Description

1,8-Naphthyridine,7-(1H-Pyrrol-1-Yl)-2,4-Bis(Trifluoromethyl)-(9Ci) is a specialized heterocyclic organic compound featuring a naphthyridine core substituted with pyrrole and trifluoromethyl groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The compound is supplied with a CAS number of 338412-21-8.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the naphthyridine scaffold.
• Material Science: Used in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient structure.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and coordination chemistry.
• Fluorescent Probe Development: The rigid, conjugated structure makes it suitable for research into fluorescent dyes and sensors for biological imaging.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental studies in heterocyclic chemistry and structure-activity relationship (SAR) exploration.

Basic Information

Product Name	1,8-Naphthyridine,7-(1H-Pyrrol-1-Yl)-2,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	338412-21-8
Molecular Formula	C15H7F6N3
Molecular Weight	343.23 g/mol
Synonyms	7-(1H-Pyrrol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 2,4-Bis(trifluoromethyl)-7-(pyrrol-1-yl)-1,8-naphthyridine; 7-(Pyrrol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 338412-21-8; 1,8-Naphthyridine, 7-(1H-pyrrol-1-yl)-2,4-bis(trifluoromethyl)-; 7-(1H-Pyrrol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (9CI)
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine derivative is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.