Description

8-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Synthesis: Serves as a core scaffold in the multi-step synthesis of complex active pharmaceutical ingredients.
• CNS Drug Development: Particularly relevant for research into neurological and psychiatric disorders due to its structural motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacology studies.

Basic Information

Product Name	8-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione
CAS No.	338408-74-5
Molecular Formula	C16H15ClF3N4O2
Molecular Weight	384.76 g/mol
Synonyms	8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione; 1,3,8-Triazaspiro[4.5]decane-2,4-dione, 8-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; CAS 338408-74-5; 338408-74-5; 8-(3-Chloro-5-trifluoromethyl-2-pyridyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
EINECS	Contact for details

Quality Control

Our 8-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.