Description

n-([(Ethylamino)Carbonyl]Oxy)-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide is a specialized fluorinated organic compound with a complex carbamate and amide structure, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in providing a versatile molecular scaffold for introducing trifluoroethoxy and reactive carbamate functionalities into target molecules. This compound is essential for research and development chemists and process engineers working in pharmaceutical development, particularly for creating novel active ingredients, and in agrochemical research for next-generation crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research & Development: Used in the creation of advanced herbicides, fungicides, or insecticides where the trifluoroethoxy groups can significantly alter biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with unique surface properties, chemical resistance, or low dielectric constants.
• Ligand Synthesis for Catalysis: Employed in the preparation of complex ligands for transition metal catalysts used in asymmetric synthesis and other high-value chemical transformations.
• Life Science Reagent: Utilized in biochemical research as a probe or modifier to study enzyme inhibition or protein interaction mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	n-([(Ethylamino)Carbonyl]Oxy)-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide
CAS No.	338395-38-3
Molecular Formula	C14H14F6N2O5
Molecular Weight	404.27 g/mol
Synonyms	2,5-Bis(2,2,2-trifluoroethoxy)-N-[(ethylcarbamoyl)oxy]benzamide; Benzenecarboxamide, N-[(ethylamino)carbonyl]oxy]-2,5-bis(2,2,2-trifluoroethoxy)-; Carbamic acid, N-(2,5-bis(2,2,2-trifluoroethoxy)benzoyl)-, ethyl ester; Ethyl N-[2,5-bis(2,2,2-trifluoroethoxy)benzoyl]carbamate
EINECS	Contact for details

Quality Control

Every batch of n-([(Ethylamino)Carbonyl]Oxy)-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with precise customer specifications and industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.