Description

1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique trifluoromethylpyridine moiety.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry and process research & development (R&D) to create novel chemical entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific target molecules under cGMP conditions.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new synthetic pathways and structure-activity relationships (SAR).

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarboxylic Acid
CAS No.	337919-65-0
Molecular Formula	C12H10ClF3N2O2
Molecular Weight	306.67 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid; 337919-65-0; 1-(3-Chloro-5-trifluoromethyl-2-pyridyl)-4-piperidinecarboxylic acid; 1-(3-Chloro-5-(trifluoromethyl)-2-pyridinyl)piperidine-4-carboxylic acid; 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid (related structure); 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.