Description

3-Bromo-4-Fluoro-n-Methylbenzamide is a high-purity, halogenated benzamide derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and fluoro substituents into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromo and fluoro groups can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes, including cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for specialty polymers.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.
• Academic and R&D Laboratories: Used in methodological studies and as a reference standard in analytical chemistry for halogenated aromatic compounds.

Basic Information

Product Name	3-Bromo-4-Fluoro-n-Methylbenzamide
CAS No.	337536-22-8
Molecular Formula	C8H7BrFNO
Molecular Weight	232.05 g/mol
Synonyms	3-Bromo-4-fluoro-N-methylbenzamide; N-Methyl-3-bromo-4-fluorobenzamide; Benzamide, 3-bromo-4-fluoro-N-methyl-; 3-Bromo-4-fluorobenzoic acid methylamide; 337536-22-8; 3-Br-4-F-N-methylbenzamide
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-4-Fluoro-n-Methylbenzamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.