Description

(S)-2-Benzyl-4-(tert-Butoxy)-4-Oxobutanoic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for the development of pharmaceuticals, particularly in the synthesis of active pharmaceutical ingredients (APIs) and complex molecules requiring specific stereochemistry. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in cardiovascular and central nervous system (CNS) drug discovery.
• Asymmetric Synthesis: Used as a starting material or intermediate in asymmetric catalytic reactions to construct complex molecules with high enantiomeric purity.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of peptidomimetics and protease inhibitors.
• Agrochemical Development: Employed in the research and production of advanced, enantiomerically pure agrochemicals such as herbicides and fungicides.
• Fine Chemical Synthesis: A versatile building block for custom synthesis and contract manufacturing of specialty chemicals and advanced materials.
• Academic & R&D: Used in university and corporate research laboratories for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(S)-2-Benzyl-4-(tert-Butoxy)-4-Oxobutanoic Acid
CAS No.	337518-87-3
Molecular Formula	C15H20O5
Molecular Weight	280.32 g/mol
Synonyms	(S)-2-Benzyl-4-(tert-butoxy)-4-oxobutanoic acid; (S)-2-Benzyl-4-(tert-butoxy)-4-oxo-butanoic acid; (S)-2-Benzyl-4-(tert-Butoxy)-4-Oxobutanoic Acid; (S)-2-Benzyl-4-(tert-Butoxy)-4-Oxobutanoic Acid CAS 337518-87-3; (S)-2-Benzyl-4-(tert-butoxycarbonyl)butanoic Acid; (S)-2-Benzyl-4-(Boc)butanoic Acid; (S)-2-Benzyl-4-(tert-Butoxycarbonyl)butyric Acid; (S)-2-Benzyl-4-(Boc)butyric Acid
EINECS	Contact for details

Quality Control

Our (S)-2-Benzyl-4-(tert-Butoxy)-4-Oxobutanoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity confirmation. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP starting material standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.