Description

3,3''-[Oxybis(Methylene)]Bis-(1S,1''S)-1,1'-Bi-2-Naphthol is a sophisticated chiral ligand and building block derived from 1,1'-Bi-2-naphthol (BINOL). This compound matters for its ability to impart high enantioselectivity in asymmetric synthesis, a critical factor in developing pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as catalytic asymmetric reactions and the synthesis of novel chiral catalysts.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or catalyst precursor in metal-catalyzed asymmetric reactions, including additions, cyclizations, and reductions.
• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Material Science: Used in the development of chiral polymers, liquid crystals, and sensors with specific optical properties.
• Agrochemical Synthesis: Applied in the research and production of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for method development and exploring new enantioselective transformations in chemistry laboratories.

Basic Information

Item	Details
Product Name	3,3''-[Oxybis(Methylene)]Bis-(1S,1''S)-1,1'-Bi-2-Naphthol
CAS No.	336800-79-4
Molecular Formula	C32H26O4
Molecular Weight	474.55 g/mol
Synonyms	(S,S)-3,3'-Bis(methoxymethyl)-1,1'-bi-2-naphthol; (S,S)-3,3'-(Oxybis(methylene))bis[1,1'-binaphthalene]-2,2'-diol; BINOL Derivative; Chiral BINOL Ether; Asymmetric Catalyst Ligand; (S)-3,3'-Dimethoxymethyl-BINOL
EINECS	Contact for details

Quality Control

Our 3,3''-[Oxybis(Methylene)]Bis-(1S,1''S)-1,1'-Bi-2-Naphthol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity (HPLC) and chemical identity confirmation (NMR, IR), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.