Description

(S)-1-(Anthracen-9-Yl)-2,2,2-Trifluoroethan-1-Amine Hydrochloride is a high-purity chiral amine derivative, synthesized as a key building block for advanced organic synthesis. Its value lies in the combination of a rigid anthracene scaffold and a trifluoromethyl group, which are critical for modulating the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Asymmetric Catalysis: Serves as a ligand or a core structure for developing novel chiral catalysts and auxiliaries in enantioselective synthesis.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the anthracene moiety can enhance binding affinity.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Fluorescent Probe Development: The anthracene core provides inherent fluorescence, making it suitable for creating sensors and imaging agents.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-1-(Anthracen-9-Yl)-2,2,2-Trifluoroethan-1-Amine Hydrochloride
CAS No.	336105-49-8
Molecular Formula	C₁₆H₁₃F₃N·HCl
Molecular Weight	327.74 g/mol
Synonyms	(S)-1-(9-Anthryl)-2,2,2-trifluoroethylamine hydrochloride; (S)-α-(Trifluoromethyl)-9-anthracenemethylamine hydrochloride; (S)-9-Anthrylethylamine, α-(trifluoromethyl)-, hydrochloride; (S)-1-(Anthracen-9-yl)-2,2,2-trifluoroethanamine hydrochloride; (S)-ATFA hydrochloride; (S)-TFAE-Amine HCl
EINECS	Contact for details

Quality Control

Our (S)-1-(Anthracen-9-Yl)-2,2,2-Trifluoroethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.