Description

1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrobromide is a high-purity, pharmaceutically relevant organic salt, serving as a critical building block in advanced chemical synthesis. This compound is valued for its unique trifluoroethylamine moiety and brominated aromatic ring, which are essential for introducing specific physicochemical properties into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromo-phenyl and trifluoroethyl groups contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for advanced polymers and specialty materials.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and biochemical tools in life sciences research.
• Custom Synthesis and Scale-Up: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrobromide
CAS No.	336105-43-2
Molecular Formula	C8H8Br2F3N
Molecular Weight	342.96 g/mol
Synonyms	4-Bromo-α-(trifluoromethyl)benzylamine hydrobromide; 1-(4-Bromophenyl)-2,2,2-trifluoroethanamine hydrobromide; (4-Bromophenyl)(trifluoromethyl)methanamine hydrobromide; 1-(4-Bromophenyl)-2,2,2-trifluoroethylamine HBr; α-(Trifluoromethyl)-4-bromobenzylamine hydrobromide; 4-Bromo-α,α,α-trifluoroethylbenzylamine hydrobromide; 2,2,2-Trifluoro-1-(4-bromophenyl)ethanaminium bromide
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each batch to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.