Description

(R)-n-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)-2-methylpropane-2-sulfinamide (Wxc04800) is a high-purity chiral sulfinamide building block, a critical intermediate in modern asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce specific chiral centers with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Asymmetric Synthesis Catalyst/Ligand: Used as a chiral auxiliary or ligand precursor in transition metal-catalyzed reactions to induce enantioselectivity.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure herbicides, fungicides, and insecticides.
• Methodology Development: Employed in academic and industrial R&D for developing new synthetic methodologies involving sulfinimines (N-sulfinyl imines).
• Fine Chemical Synthesis: Utilized in the production of other specialty chemicals and complex organic molecules requiring the specific stereochemistry this compound provides.

Basic Information

Product Name	(R)-n-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)-2-methylpropane-2-sulfinamide (Wxc04800)
CAS No.	336105-31-8
Molecular Formula	C₁₂H₁₅BrF₃NOS
Molecular Weight	358.22 g/mol
Synonyms	(R)-N-[(1S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl]-2-methylpropane-2-sulfinamide; (R)-tert-Butanesulfinamide, N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-; WXC-04800; Wxc04800; (R)-2-Methyl-N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]propane-2-sulfinamide; Chiral Sulfinamide Intermediate; (R)-N-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)-2-methyl-2-propanesulfinamide
EINECS	Contact for details

Quality Control

Our (R)-n-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)-2-methylpropane-2-sulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when necessary for prolonged exposure to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.