Description

Spiro[2H-Indene-2,3-Pyrrolidin]-5-One, 1,3,3A,4,5,6,7,7A-Octahydro-, Stereoisomer (9Ci) is a complex spirocyclic organic compound that serves as a versatile and high-value synthetic intermediate. Its unique fused ring system, containing both indene and pyrrolidinone motifs, makes it a critical building block for constructing sophisticated molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its complex stereochemistry for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and novel heterocyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Catalyst Ligand Development: The spirocyclic structure can be functionalized to create novel ligands for asymmetric catalysis.

Basic Information

Product Name	Spiro[2H-Indene-2,3-Pyrrolidin]-5-One, 1,3,3A,4,5,6,7,7A-Octahydro-, Stereoisomer (9Ci)
CAS No.	335671-45-9
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	1,3,3a,4,5,6,7,7a-Octahydrospiro[2H-indene-2,3'-pyrrolidin]-5-one; Octahydrospiro[indene-2,3'-pyrrolidin]-5-one; Spiro[indane-1,3'-pyrrolidine]-2',5-dione (hydrogenated derivative); 335671-45-9; Spirocyclic pyrrolidinone indane derivative.
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a commitment to cGMP (current Good Manufacturing Practice) standards where applicable for pharmaceutical development. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. Our rigorous quality testing utilizes advanced analytical techniques including HPLC, GC, NMR, and chiral chromatography to ensure consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.