Description

Spiro[2H-Indene-2,3-Pyrrolidin]-5-One, Octahydro-, (3Ar,6Ar)-Rel- (9Ci) is a complex spirocyclic organic compound with the CAS registry number 335458-42-9. This specialized intermediate is valued for its unique three-dimensional structure, which makes it a critical building block in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, high-performance pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis Ligand Precursor: Serves as a sophisticated precursor for ligands used in chiral catalysis to induce stereoselectivity in chemical reactions.
• Material Science Research: Investigated for the development of novel organic frameworks and functional materials with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	Spiro[2H-Indene-2,3-Pyrrolidin]-5-One, Octahydro-, (3Ar,6Ar)-Rel- (9Ci)
CAS No.	335458-42-9
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	rel-(3aR,6aR)-Octahydrospiro[indene-2,3'-pyrrolidin]-5-one; Octahydrospiro[indene-2,3'-pyrrolidin]-5-one, rel-(3aR,6aR)-; (3aR,6aR)-rel-Octahydrospiro[indene-2,3'-pyrrolidin]-5-one; Spiro[indene-2,3'-pyrrolidin]-5-one, octahydro-, (3aR,6aR)-rel-; 335458-42-9; Advanced spirocyclic amine ketone; Chiral spiro[indene-pyrrolidinone] building block.
EINECS	Contact for details

Quality Control

Every batch of Spiro[2H-Indene-2,3-Pyrrolidin]-5-One, Octahydro-, (3Ar,6Ar)-Rel- (9Ci) is produced and tested under a strict quality management system. We ensure high chiral purity and chemical consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.