Description

tert-Butyl (4-Iodo-2-Nitrophenyl)Carbamate is a specialized organic building block featuring a carbamate-protected aniline core with iodine and nitro substituents. This compound matters as a versatile and high-value intermediate, enabling precise synthetic modifications in complex molecule construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized aniline derivative.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing diverse compound libraries via cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides that incorporate halogenated aromatic systems.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials requiring specific electronic properties.
• Chemical Biology: Can be utilized as a probe or linker in bioconjugation strategies due to its reactive iodine handle.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	tert-Butyl (4-Iodo-2-Nitrophenyl)Carbamate
CAS No.	335254-69-8
Molecular Formula	C11H13IN2O4
Molecular Weight	364.14 g/mol
Synonyms	Boc-4-Iodo-2-nitroaniline; tert-Butyl N-(4-iodo-2-nitrophenyl)carbamate; 1-(tert-Butoxycarbonylamino)-4-iodo-2-nitrobenzene; 4-Iodo-2-nitroaniline N-Boc derivative; Carbamic acid, N-(4-iodo-2-nitrophenyl)-, 1,1-dimethylethyl ester; Boc-protected 4-iodo-2-nitroaniline; (4-Iodo-2-nitrophenyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Iodo-2-Nitrophenyl)Carbamate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.