Description

3-Bromocinnolin-4(1H)-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the synthesis of specialized chemical libraries.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicide and pesticide candidates, leveraging the cinnoline scaffold for bioactivity.
• Material Science Precursor: Acts as a building block for creating organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in heterocyclic chemistry and cross-coupling reactions.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) producing custom fine chemicals for client projects.

Basic Information

Product Name	3-Bromocinnolin-4(1H)-One
CAS No.	335242-55-2
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	3-Bromo-1,4-dihydrocinnolin-4-one; 3-Bromo-4(1H)-cinnolinone; 3-Bromocinnolin-4-ol; 4-Hydroxy-3-bromocinnoline; 3-Bromo-4-hydroxycinnoline; 3-Bromo-1H-cinnolin-4-one; 3-Brom-4(1H)-cinnolinon (German); 3-ブロモ-4(1H)-シンノリンン (Japanese)
EINECS	Contact for details

Quality Control

Our 3-Bromocinnolin-4(1H)-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceability supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment. Recommended storage temperature is 2-8°C for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.