Description

(R)-3-Piperidinamine Dihydrochloride is a high-purity chiral amine building block essential for pharmaceutical research and development. Its defined stereochemistry and dihydrochloride salt form provide excellent stability and solubility for synthetic applications. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and potential APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in enantioselective catalysis.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological targets and pathways.
• Process Chemistry & Scale-up: Used in the development and optimization of scalable synthetic routes for advanced intermediates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-3-Piperidinamine Dihydrochloride
CAS No.	334618-23-4
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	(R)-3-Aminopiperidine Dihydrochloride; (3R)-3-Piperidinamine Dihydrochloride; (R)-3-Piperidinamine Hydrochloride (1:2); (R)-3-Amino-piperidine Dihydrochloride; (R)-3-Piperidinammonium Chloride; (R)-3-Piperidinylamine Dihydrochloride; (R)-3-Piperidinamine, Hydrochloride; (R)-3-Piperidinamine, Dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-Piperidinamine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles. We adhere to relevant industry standards and can provide material for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.