Description

2,3-Difluoro-6-Iodobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, prized for its unique substitution pattern that enables selective cross-coupling and functionalization reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecules for drug discovery and specialty chemical applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the iodine atom for further derivatization.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, such as Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where halogenated aromatic cores are required.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in organic chemistry, exploring new fluorination and iodination strategies.

Basic Information

Product Name	2,3-Difluoro-6-Iodobenzoic Acid
CAS No.	333780-75-9
Molecular Formula	C7H3F2IO2
Molecular Weight	283.00 g/mol
Synonyms	6-Iodo-2,3-difluorobenzoic Acid; 2,3-Difluoro-6-iodobenzoic Acid; Benzoic acid, 2,3-difluoro-6-iodo-; 333780-75-9; 2,3-Difluoro-6-iodo-benzoic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Iodobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.