Description

N3-Asp(Tbu)-Oh (Dicyclohexylammonium) Salt is a protected aspartic acid derivative, specifically formulated as a dicyclohexylammonium salt to enhance its stability and handling properties for advanced chemical synthesis. This compound serves as a crucial building block in the production of complex peptides and other bioactive molecules, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid derivative for the controlled incorporation of aspartic acid into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins in solution.
• Medicinal Chemistry & Drug Discovery: A vital intermediate for constructing peptide-based drug candidates and molecular probes.
• Bioconjugation: Employed in the site-specific modification of proteins and other biomolecules via its azido (N3) functional group.
• Chemical Biology Research: Used in the study of protein-protein interactions and the development of activity-based probes.
• Production of Custom Peptides: A fundamental reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) specializing in peptide services.

Basic Information

Product Name	N3-Asp(Tbu)-Oh (Dicyclohexylammonium) Salt
CAS No.	333366-23-7
Molecular Formula	C20H39N5O4
Molecular Weight	413.56 g/mol
Synonyms	N3-Asp(OtBu)-OH DCHA Salt; Azidoaspartic acid tert-butyl ester dicyclohexylammonium salt; (2S)-2-[(2-Azidoacetyl)amino]-4-(tert-butoxy)-4-oxobutanoic acid dicyclohexylammonium salt; N3-Asp(OtBu)-OH·DCHA; Fmoc-Asp(OtBu)-OH precursor; Aspartic acid derivative, N3-protected; Peptide synthesis building block CAS 333366-23-7
EINECS	Contact for details

Quality Control

Our N3-Asp(Tbu)-Oh (Dicyclohexylammonium) Salt is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Allow the container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Specific Rotation	Contact for details
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.