Description

4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-1-Methyl-,(1S,7As)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate (API) with the CAS number 332940-40-6. This compound is valued for its complex, fused-ring structure which serves as a critical chiral building block in modern organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, fragrances, and other high-value organic compounds requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological development and as a reference standard in synthetic organic chemistry research.

Basic Information

Product Name	4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-1-Methyl-,(1S,7As)-(9Ci)
CAS No.	332940-40-6
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(1S,7aS)-1-Methyl-1,2,5,6,7,7a-hexahydro-4H-inden-4-one; (1S,7aS)-1-Methyloctahydro-4H-inden-4-one; 1-Methyl-1,2,5,6,7,7a-hexahydro-4H-inden-4-one, (1S,7aS)-; 4H-Inden-4-one, 1,2,5,6,7,7a-hexahydro-1-methyl-, (1S,7aS)-; (1S,7aS)-1-Methyl-4,5,6,7-tetrahydro-1H-inden-4-one; Hexahydro-1-methyl-4H-inden-4-one (stereoisomer); Chiral Hexahydroindenone Derivative
EINECS	Contact for details

Quality Control

Our 4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-1-Methyl-,(1S,7As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and cGMP-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.