Description

5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Butyric Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 332884-21-6. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its specific naphthyridine core structure. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in multi-step synthesis routes for complex APIs.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: May be employed as a ligand or scaffold in biochemical assays and probe development.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Butyric Acid
CAS No.	332884-21-6
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid; 2-(5,6,7,8-Tetrahydro[1,8]naphthyridin-2-yl)butyric acid; 5,6,7,8-Tetrahydro-1,8-naphthyridine-2-butyric acid; THN-2-Butyric Acid; 332884-21-6; 1,8-Naphthyridine-2-butyric acid, 5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.