Description

2-[(6-Bromo-4-Oxo-3-Phenyl-3,4-Dihydroquinazolin-2-Yl)Sulfanyl]-n-(4-Bromophenyl)Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of proprietary drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex quinazolinone-based molecular libraries.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-[(6-Bromo-4-Oxo-3-Phenyl-3,4-Dihydroquinazolin-2-Yl)Sulfanyl]-n-(4-Bromophenyl)Acetamide
CAS No.	332412-42-7
Molecular Formula	C22H15Br2N3O2S
Molecular Weight	545.25 g/mol
Synonyms	2-[(6-Bromo-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)sulfanyl]-N-(4-bromophenyl)acetamide; 2-((6-Bromo-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)-N-(4-bromophenyl)acetamide; N-(4-Bromophenyl)-2-((6-bromo-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide; 332412-42-7; Acetamide, 2-[(6-bromo-4-oxo-3-phenyl-3,4-dihydro-2-quinazolinyl)thio]-N-(4-bromophenyl)-; Light-sensitive (store away from light)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency suitable for pharmaceutical R&D and scale-up. Each lot is subjected to comprehensive analytical characterization, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.