Description

(2'S)-4-Hydroxy-2,2',6-Trimethyl-Benzenepropanoic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in stereoselective routes.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex molecular architectures requiring specific stereochemistry.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and performance materials.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	(2'S)-4-Hydroxy-2,2',6-Trimethyl-Benzenepropanoic Acid
CAS No.	332186-76-2
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	(S)-4-Hydroxy-2,2',6-trimethylbenzenepropanoic acid; (2'S)-HTPA; 2-(2-Hydroxy-3,5-dimethylphenyl)propanoic acid (enantiomer); Benzenepropanoic acid, 4-hydroxy-2,2',6-trimethyl-, (2'S)-; (S)-2-(2-Hydroxy-3,5-dimethylphenyl)propionic acid; (S)-α-Methyl-2-hydroxy-3,5-dimethylbenzeneacetic acid; (S)-HTPA
EINECS	Contact for details

Quality Control

Our (2'S)-4-Hydroxy-2,2',6-Trimethyl-Benzenepropanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.