Description

4-(6-Methyl-4-Phenylquinazolin-2-Yl)Piperazine-1-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinazoline-piperazine hybrid structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly those targeting kinase inhibition and other key biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Kinase Inhibitor Development: Used as a core scaffold for designing and synthesizing potential kinase inhibitors due to the quinazoline moiety.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-(6-Methyl-4-Phenylquinazolin-2-Yl)Piperazine-1-Carbaldehyde
CAS No.	332102-15-5
Molecular Formula	C20H20N4O
Molecular Weight	332.40 g/mol
Synonyms	4-(6-Methyl-4-phenylquinazolin-2-yl)piperazine-1-carboxaldehyde; 1-Formyl-4-(6-methyl-4-phenyl-2-quinazolinyl)piperazine; 4-(6-Methyl-4-phenylquinazolin-2-yl)piperazine-1-carbaldehyde; Piperazine-1-carbaldehyde, 4-(6-methyl-4-phenyl-2-quinazolinyl)-; 332102-15-5; 4-(6-Methyl-4-phenyl-2-quinazolinyl)-1-piperazinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-(6-Methyl-4-Phenylquinazolin-2-Yl)Piperazine-1-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.