Description

2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline-pyrimidine hybrid class of heterocyclic compounds. This compound matters for its critical role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. Pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions need this material for synthesizing potential drug candidates with specific biological activity profiles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for cancer therapy and other proliferative diseases.
• Chemical Biology Probes: Serves as a core scaffold for creating molecular probes to study biological pathways and protein functions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for fundamental research in heterocyclic chemistry and drug discovery projects.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One
CAS No.	332074-12-1
Molecular Formula	C₁₅H₁₅N₅O
Molecular Weight	281.31 g/mol
Synonyms	2-[(4,7-Dimethyl-2-quinazolinyl)amino]-6-methyl-4(3H)-pyrimidinone; 6-Methyl-2-[(4,7-dimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one; 2-((4,7-Dimethylquinazolin-2-yl)amino)-6-methylpyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-[(4,7-dimethyl-2-quinazolinyl)amino]-6-methyl-; Quinazoline-pyrimidine hybrid intermediate; CAS 332074-12-1
EINECS	Contact for details

Quality Control

Our 2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profile. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.