Description

(S)-3-Amino-4-(3-Thienyl)-Butyric Acid-Hcl CAS NO 332061-92-4 is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of a thiophene-containing β-amino acid. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), peptidomimetics, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Peptidomimetic Chemistry: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Research: A valuable tool compound for studying enzyme mechanisms, receptor-ligand interactions, and metabolic pathways.
• Agrochemical Development: Potential intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Material Science: Exploration as a monomer for specialty polymers with unique electronic or optical properties derived from the thiophene moiety.

Basic Information

Product Name	(S)-3-Amino-4-(3-Thienyl)-Butyric Acid Hydrochloride
CAS No.	332061-92-4
Molecular Formula	C8H12ClNO2S
Molecular Weight	221.70 g/mol
Synonyms	(S)-3-Amino-4-(3-thienyl)butanoic acid hydrochloride; (3S)-3-Amino-4-(thiophen-3-yl)butanoic acid hydrochloride; (S)-3-Amino-4-(3-thienyl)butyric acid HCl; 3-Thiophenebutanoic acid, 3-amino-, hydrochloride, (3S)-; 332061-92-4; (S)-AABA(3-Thienyl)-HCl
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(3-Thienyl)-Butyric Acid-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.