Description

(R)-3-Amino-4-(2-Thienyl)-Butyric Acid-Hcl CAS NO 332061-91-3 is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, enabling the development of enantiomerically pure active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Peptide Synthesis: Used as a protected or unprotected amino acid derivative in the solid-phase and solution-phase synthesis of bioactive peptides and peptidomimetics.
• Asymmetric Catalysis Research: Valuable starting material or ligand precursor in the development of new asymmetric synthetic methodologies.
• Agrochemical Development: Intermediate in the synthesis of chiral active ingredients for crop protection products, leveraging its specific stereochemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory and R&D laboratories.

Basic Information

Product Name	(R)-3-Amino-4-(2-Thienyl)-Butyric Acid Hydrochloride
CAS No.	332061-91-3
Molecular Formula	C8H12ClNO2S
Molecular Weight	221.70 g/mol
Synonyms	(R)-3-Amino-4-(2-thienyl)butanoic acid hydrochloride; (R)-3-Amino-4-(thiophen-2-yl)butyric acid HCl; (R)-β-Amino-4-(2-thienyl)butyric acid hydrochloride; (R)-3-AATBA-HCl; (R)-Amino thienyl butyric acid HCl; (R)-4-(2-Thienyl)-3-aminobutanoic acid hydrochloride; (R)-3-Amino-4-(2-thienyl)butyric acid monohydrochloride
EINECS	Contact for details

Quality Control

Our production of (R)-3-Amino-4-(2-Thienyl)-Butyric Acid-Hcl adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.