Description

3-Allyl-2-Thioxo-2,3,5,6-Tetrahydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(1H)-One is a sophisticated spiro-fused heterocyclic compound that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique molecular architecture, featuring a quinazoline core fused with a cyclopentane ring, makes it a valuable precursor for developing novel pharmacologically active molecules and functional materials. This high-purity intermediate is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Organic Synthesis & Catalysis: A versatile intermediate for constructing complex heterocyclic frameworks in academic and industrial R&D settings.
• Material Science: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Allyl-2-Thioxo-2,3,5,6-Tetrahydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(1H)-One
CAS No.	332024-52-9
Molecular Formula	C19H20N2OS
Molecular Weight	324.44 g/mol
Synonyms	3-Allyl-2-thioxo-2,3,5,6-tetrahydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-4(1H)-one; Spiro[cyclopentane-1,5'-[5H]benzo[h]quinazoline]-4'(1'H)-one, 3'-allyl-2'-thioxo-2',3'-dihydro-; 3-Allyl-2-thioxo-1,2,3,5,6,11-hexahydrospiro[benzo[h]quinazoline-5,1'-cyclopentan]-4-one; 332024-52-9; Allyl-spiro-thioxoquinazolinone; AS-TQ Intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-Allyl-2-Thioxo-2,3,5,6-Tetrahydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.