Description

3-Allyl-2-(Methylsulfanyl)-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclohexane)-4(3H)-One is a sophisticated spirocyclic quinazolinone derivative, a high-value chemical intermediate prized for its unique molecular architecture. This compound matters for its role as a critical building block in advanced organic synthesis, enabling the development of novel compounds with targeted properties. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct intricate polycyclic frameworks due to its spirocyclic and quinazolinone motifs.
• Agrochemical Research: Potential intermediate for developing new active ingredients with herbicidal or pesticidal properties.
• Material Science Exploration: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	3-Allyl-2-(Methylsulfanyl)-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclohexane)-4(3H)-One
CAS No.	332024-46-1
Molecular Formula	C20H24N2OS
Molecular Weight	340.48 g/mol
Synonyms	3-Allyl-2-(methylthio)-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(3H)-one; 2-(Methylsulfanyl)-3-(2-propen-1-yl)-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclohexane]-4(3H)-one; Spiro[cyclohexane-1,5'-[5,6]dihydrobenzo[h]quinazoline]-4'(3'H)-one, 3'-allyl-2'-(methylthio)-; CAS 332024-46-1
EINECS	Contact for details

Quality Control

Our 3-Allyl-2-(Methylsulfanyl)-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclohexane)-4(3H)-One is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.