Description

(R)-3-Amino-4-(2-Naphthyl)-Butyric Acid-Hcl CAS NO 331847-02-0 is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and intermediate in the synthesis of complex, biologically active molecules. It is essential for research and development in the pharmaceutical and fine chemical industries, where precise stereochemistry is paramount for drug efficacy and safety. Its unique structure makes it valuable for creating novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and enzyme inhibitors.
• Peptide Synthesis: Used as a protected or unprotected amino acid derivative in the solid-phase and solution-phase synthesis of novel peptides with potential therapeutic applications.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of chiral catalysts for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, activity-based probes (ABPs), and other tools for studying enzyme function and protein interactions.
• Agrochemical Development: Acts as an intermediate in the synthesis of chiral agrochemicals, such as herbicides and fungicides, where specific stereochemistry can influence activity and environmental profile.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	(R)-3-Amino-4-(2-Naphthyl)-Butyric Acid Hydrochloride
CAS No.	331847-02-0
Molecular Formula	C₁₄H₁₆ClNO₂
Molecular Weight	265.73 g/mol
Synonyms	(R)-3-Amino-4-(naphthalen-2-yl)butanoic acid hydrochloride; (R)-3-Amino-4-(2-naphthyl)butyric acid HCl; (R)-β-Amino-2-naphthalenebutanoic acid hydrochloride; (3R)-3-Amino-4-(naphthalen-2-yl)butanoic acid hydrochloride; (R)-3-Amino-4-(2-naphthalenyl)butanoic acid hydrochloride; D-3-Amino-4-(2-naphthyl)butyric acid hydrochloride; (R)-AABA(2-Naphthyl)-HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-4-(2-Naphthyl)-Butyric Acid-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development with custom purity grades and specifications aligned with cGMP principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.