Description

(S)-3-Amino-4-(3-Methylphenyl)-Butyric Acid-Hcl CAS NO 331846-93-6 is a high-purity chiral intermediate featuring a phenylalanine derivative backbone. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by pharmaceutical R&D departments, contract manufacturing organizations (CMOs), and fine chemical producers for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptide Mimetic Synthesis: Used in the development of peptidomimetics and constrained amino acid analogs for drug design.
• Protease Inhibitor Development: Serves as a core structure in the research and production of enzyme inhibitors.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral auxiliary in stereoselective synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Bioconjugation Chemistry: The amino and carboxylic acid functional groups enable its use in linker chemistry for antibody-drug conjugates (ADCs) or other bioconjugates.

Basic Information

Product Name	(S)-3-Amino-4-(3-Methylphenyl)-Butyric Acid Hydrochloride
CAS No.	331846-93-6
Molecular Formula	C11H15NO2 • HCl
Molecular Weight	229.70 g/mol (Free base: 193.24 g/mol)
Synonyms	(S)-3-Amino-4-(3-methylphenyl)butanoic acid hydrochloride; (S)-3-Amino-4-(m-tolyl)butyric acid HCl; (S)-3-Amino-4-(3-methylphenyl)butyric acid hydrochloride; (S)-3-Amino-4-(3-tolyl)butanoic acid hydrochloride; (S)-β-Amino-m-methylhydrocinnamic acid hydrochloride; (S)-3-Amino-4-(3'-methylphenyl)butanoic acid HCl; L-3-Amino-4-(3-methylphenyl)butyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(3-Methylphenyl)-Butyric Acid-Hcl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (Anhydrous basis)
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.