Description

(S)-3-Amino-4-(4-Nitrophenyl)Butyric Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel APIs, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to construct complex molecular architectures.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of peptide-like molecules for drug discovery.
• Agrochemical Development: Employed in the synthesis of chiral active ingredients for herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Useful for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-3-Amino-4-(4-Nitrophenyl)Butyric Acid Hydrochloride
CAS No.	331763-77-0
Molecular Formula	C10H13N2O4 • HCl
Molecular Weight	272.68 g/mol (Free base: 236.22 g/mol)
Synonyms	(S)-3-Amino-4-(4-nitrophenyl)butanoic acid hydrochloride; (3S)-3-Amino-4-(4-nitrophenyl)butyric acid HCl; (S)-4-(4-Nitrophenyl)-3-aminobutanoic acid hydrochloride; (S)-γ-Amino-4-nitrophenylbutyric acid hydrochloride; (S)-3-Amino-4-(p-nitrophenyl)butyric acid hydrochloride; (S)-H-APBA-OH • HCl; (S)-AABA(4-NO2) • HCl
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(4-Nitrophenyl)Butyric Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.