Description

(S)-3-Amino-4-(4-Bromophenyl)Butyric Acid Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its defined stereochemistry and reliable quality, which are critical for ensuring the efficacy and safety of final drug products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Research: Used in the development of inhibitors for enzymes like γ-secretase and BACE-1, relevant to neurological conditions.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for constructing biologically active peptide mimics.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Process Chemistry & Scale-up: Supports route development and optimization for the commercial manufacturing of complex drug molecules.

Basic Information

Item	Detail
Product Name	(S)-3-Amino-4-(4-Bromophenyl)Butyric Acid Hydrochloride
CAS No.	331763-71-4
Molecular Formula	C10H13BrClNO2
Molecular Weight	294.57 g/mol
Synonyms	(S)-3-Amino-4-(4-bromophenyl)butanoic acid hydrochloride; (3S)-3-Amino-4-(4-bromophenyl)butyric acid hydrochloride; (S)-3-Amino-4-(p-bromophenyl)butyric acid HCl; γ-Amino-β-(4-bromophenyl)-L-homobutyric acid hydrochloride; L-3-Amino-4-(4-bromophenyl)butanoic acid hydrochloride; (S)-4-(4-Bromophenyl)-3-aminobutanoic acid hydrochloride; ABPBA hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(4-Bromophenyl)Butyric Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.