Description

2-Chloro-8-Bromoquinazolin-4(3H)-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating new bioactive molecules, especially kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A critical scaffold for the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Kinase Inhibitor Development: Serves as a core structure for designing and synthesizing novel small-molecule kinase inhibitors.
• Agrochemical Research: Used in the discovery and development of new herbicides and fungicides.
• Material Science: A building block for creating specialized organic ligands and functional polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for clients.

Basic Information

Product Name	2-Chloro-8-Bromoquinazolin-4(3H)-One
CAS No.	331647-04-2
Molecular Formula	C8H4BrClN2O
Molecular Weight	259.49 g/mol
Synonyms	8-Bromo-2-chloro-3,4-dihydro-4-oxoquinazoline; 2-Chloro-8-bromo-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-chloro-8-bromo-; 331647-04-2; 8-Bromo-2-chloroquinazolin-4(3H)-one; 2-Chloro-8-bromoquinazolin-4-ol; 2-Chloro-8-bromo-3,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Bromoquinazolin-4(3H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.