Description

8-Bromoquinazoline-2,4(1H,3H)-Dione is a high-purity brominated quinazoline derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel quinazoline-based drug candidates, particularly for oncology and kinase inhibitor research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research: Acts as a fundamental building block in academic and industrial laboratories for exploring new organic reactions and creating compound libraries.
• Material Science: Investigated for the synthesis of specialized organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Dye & Pigment Synthesis: Utilized in the development of novel heterocyclic dyes and functional colorants.

Basic Information

Product Name	8-Bromoquinazoline-2,4(1H,3H)-Dione
CAS No.	331646-99-2
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	8-Bromoquinazoline-2,4-dione; 8-Bromo-2,4-dihydroxyquinazoline; 8-Bromo-1H-quinazoline-2,4-dione; 8-Bromoquinazoline-2,4(1H,3H)-dione; 2,4(1H,3H)-Quinazolinedione, 8-bromo-; 8-Bromoquinazoline-2,4-diol; 8-Bromo-2,4-quinazolinediol
EINECS	Contact for details

Quality Control

Our 8-Bromoquinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.